1. Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA. Blakney AK et al. 2019. Gene Therapy Self-amplifying RNA (saRNA) therapies are at the forefront of new vaccine design, as they have been used to treat diseases like HIV or cancer. To make their effect saRNA molecules must go through the membrane of … Read More
A molecule with a destiny: modelling drug delivery in IBD
Since a drug enters our body, it will complete a journey inside it that is full of difficulties. For example, when we take an aspirin, the analgesic molecules have to go all the way from the mouth to the pain location, facing, among other hazards, the harsh conditions of the stomach. Regardless of how the drug is administered, it must … Read More
