Dining With Inflammatory Bowel Disease: A Review of the Literature on Diet in the Pathogenesis and Management of IBD. Gu P. and Feagins LA. 2020. Inflammatory Bowel Diseases. 26 (2): 181–191.
Inflammatory Bowel Disease (IBD) prevalence has increased worldwide over the last half-century. However, the causes of this pathology are still largely unknown. IBD aetiology involves a complex interaction between genetic and environmental factors, making it hard to find adequate treatment options. Among these environmental factors, the diet may play a central role in IBD, as food compounds interact directly with epithelial and immune cells, as well as with gut microbiota. Therefore, studying the relationship between IBD and diet may pave the way for nutritional interventions to prevent and treat this condition, together with the already available pharmacological therapies used to treat IBD symptoms.
In this review, the authors analyse the available data on the role of diet in the pathogenesis and treatment of IBD. Particularly, they discuss the effects that food such as meat, fat, fibre and emulsifiers—the main components of western diet—may have in the intestinal homeostasis. Finally, they describe novel nutritional interventions and assess their effectiveness in different studies.